DefenCath® (taurolidine and heparin) catheter lock solution is indicated to reduce the incidence of catheter-related bloodstream infections (CRBSI) in adult patients with kidney failure receiving chronic hemodialysis (HD) through a central venous catheter (CVC). This drug is indicated for use in a limited and specific population of patients.


Berkeley Heights, NJ – May 11, 2020 – CorMedix Inc. (NYSE American: CRMD), a biopharmaceutical
company focused on developing and commercializing therapeutic products for the prevention and
treatment of infectious and inflammatory disease, today announced that it has appointed Matt David,
M.D. as the Company’s Executive Vice President and Chief Financial Officer. Dr. David will participate in
the Company’s Conference Call discussing its First Quarter 2020 financial results and recent corporate
developments today at 4:30pm Eastern time.

“I am pleased that Matt has agreed to join the Company at this most exciting time,” said Khoso Baluch,
CorMedix Chief Executive Officer. “With his medical background and his significant experience in
healthcare capital markets and strategy, he will fill an important role as we continue our preparations to
commercialize Neutrolin, whether on our own or with a strategic or commercial partner.”

Dr. David was most recently Head of Strategy at Ovid Therapeutics, a Nasdaq-listed biopharmaceutical
company focused on rare neurological diseases. In addition to his recent experience in industry, Dr. David
has more than 15 years of experience in finance as a healthcare investment banker and earlier as an equity
analyst covering the pharma sector.

“I am thrilled to be joining CorMedix at such an exciting time for the Company,” commented Dr. David.
“As Neutrolin approaches a potential regulatory approval later this year, the Company will face a range of
strategic decisions all aimed at bringing Neutrolin to patients who can benefit from it as expeditiously as
possible. I am excited by the prospects of this novel product in the substantial hemodialysis market and
look forward to working with the broader CorMedix team.”

Dr. David earned his M.D. from NYU School of Medicine and was a surgery resident at Beth Israel Hospital.
He received his undergraduate degree in Chemistry from Dartmouth College.

About CorMedix
CorMedix Inc. is a biopharmaceutical company focused on developing and commercializing therapeutic
products for the prevention and treatment of infectious and inflammatory diseases. The Company is
focused on developing its lead product Neutrolin®, a novel, non-antibiotic antimicrobial solution designed
to prevent costly and dangerous bloodstream infections associated with the use of central venous
catheters for the U.S. market. The Company completed a Phase 3 clinical trial of Neutrolin in patients
undergoing chronic hemodialysis, which showed a 71% reduction in catheter-related bloodstream
infections (CRBSIs) relative to the heparin control arm (p=0.0006) with a good safety profile. Such
infections cost the U.S. healthcare system approximately $6 billion annually and contribute significantly
to increased morbidity and mortality. Neutrolin has FDA Fast Track status and is designated as a Qualified
Infectious Disease Product, which provides the potential for priority review of a marketing application by
FDA and allows for 5 additional years of QIDP market exclusivity in the event of U.S. approval. FDA has
granted rolling submission and review of portions of the new drug application (NDA) and CorMedix has
begun submission of the NDA. Neutrolin is already marketed as a CE Marked product in Europe and other
territories. In parallel, CorMedix is leveraging its taurolidine technology to develop a pipeline of
antimicrobial medical devices, with active programs in surgical sutures and meshes, and topical hydrogels.
The company is also working with top-tier researchers to develop taurolidine-based therapies for rare
pediatric cancers. For more information, visit:

Forward-Looking Statements
This press release contains forward-looking statements within the meaning of the Private Securities
Litigation Reform Act of 1995 that are subject to risks and uncertainties. All statements, other than
statements of historical facts, regarding management’s expectations, beliefs, goals, plans or CorMedix’s
prospects, future financial position, financing plans, future revenues and projected costs should be
considered forward-looking. Readers are cautioned that actual results may differ materially from
projections or estimates due to a variety of important factors, including: the results of our discussions
with the FDA regarding the Neutrolin development path, including whether a second Phase 3 clinical trial
for Neutrolin will be required; the resources needed to complete the information required to submit a
new drug application for Neutrolin to the FDA; the risks and uncertainties associated with CorMedix’s
ability to manage its limited cash resources and the impact on current, planned or future research,
including the continued development of Neutrolin and research for additional uses for taurolidine;
obtaining additional financing to support CorMedix’s research and development and clinical activities and
operations; preclinical results are not indicative of success in clinical trials and might not be replicated in
any subsequent studies or trials; and the ability to retain and hire necessary personnel to staff our
operations appropriately. At this time, we are unable to assess whether, and to what extent, the
uncertainty surrounding the Coronavirus pandemic may impact our business and operations. These and
other risks are described in greater detail in CorMedix’s filings with the SEC, copies of which are available
free of charge at the SEC’s website at or upon request from CorMedix. CorMedix may not
actually achieve the goals or plans described in its forward-looking statements, and investors should not
place undue reliance on these statements. CorMedix assumes no obligation and does not intend to update
these forward-looking statements, except as required by law.

Investor Contact:
Dan Ferry
Managing Director
LifeSci Advisors